Ohio air show resumes after stuntwoman, pilot die

A stunt plane loses control as a wing walker performs at the Vectren Air Show just before crashing, Saturday, June 22, 2013, in Dayton, Ohio. The crash killed the pilot and the stunt walker instantly, authorities said. (AP Photo/Thanh V Tran)

A stunt plane loses control as a wing walker performs at the Vectren Air Show just before crashing, Saturday, June 22, 2013, in Dayton, Ohio. The crash killed the pilot and the stunt walker instantly, authorities said. (AP Photo/Thanh V Tran)

Flames erupt from a plane after a stunt plane crashed while performing with a wing walker at the Vectren Air Show, Saturday, June 22, 2013, in Dayton, Ohio. The crash killed the pilot and the wing walker instantly, authorities said. (AP Photo/Thanh V Tran)

A wing walker performs at the Vectren Air Show just before crashing, Saturday, June 22, 2013, in Dayton, Ohio. The crash killed the pilot and the stunt walker instantly, authorities said. (AP Photo/Thanh V Tran)

Flames erupt from a plane after it crashed at the Vectren Air Show at the airport in Dayton, Ohio. The crash killed the pilot and stunt walker on the plane instantly, authorities said. (AP Photo/Dayton Daily News, Ty Greenlees)

This photo provided provided WHIO TV shows a plane after it crashed Saturday, June 22, 2013, at the Vectren Air Show near Dayton, Ohio. There was no immediate word on the fate of the pilot, wing walker or anyone else aboard the plane. No one on the ground was hurt. (AP Photo/WHIO-TV)

CINCINNATI (AP) ? An air show in southwestern Ohio reopened with a moment of silence Sunday, a day after a pilot and wing walker died in a horrifying, fiery crash in front of thousands of spectators.

The Vectren Air Show near Dayton, which closed right after Saturday's crash, resumed Sunday in honor of pilot Charlie Schwenker and veteran stuntwoman Jane Wicker, both of Virginia.

"As a pilot, you accept the fact that accidents do happen ? it's an accepted risk we take," said John King, president of the Flying Circus Airshow, which had trained Wicker.

"They were both dedicated to flying and the act. They were true, ultimate professionals," King said. "I don't know of anyone who could have done any better than what they were doing."

Wicker and Schwenker were killed when their plane crashed in front of spectators who screamed in shock as the aircraft became engulfed in flames. No one else was hurt.

Video of the crash showed their plane gliding through the sky before abruptly rolled over, crashing and exploding into flames. Wicker, performing at the Dayton show for the first time, had been sitting atop the 450 HP Stearmans.

The decision to resume the show a day after the crash was an emotional one supported by Wicker's ex-husband, said air show general manager Brenda Kerfoot.

"He said, 'This is what Jane and Charlie would have wanted,'" Kerfoot said. "'They want you to have a safe show and go out there and do what you do best.'"

Wicker, 44, who lived in Bristow, Va., was a mother of two boys and engaged to be married, Kerfoot said.

"She was a well-rounded, delightful woman who was passionate about aviation," said Kerfoot. "She was in the business for a very long time and was well-loved by the air show community; she would certainly have wanted the show to go on."

Schwenker, 64, of Oakton, Va., was married.

The cause of the crash is unclear and the conclusion of an investigation by the National Transportation Safety Board likely will take months. The NTSB planned a mid-afternoon news conference Sunday to discuss the accident.

Wicker's website says she responded to a classified ad from the Flying Circus Airshow in Bealeton, Va., in 1990, for a wing-walking position, thinking it would be fun. She was a contract employee who worked as a Federal Aviation Administration budget analyst, the FAA said.

In one post on Wicker's site, the stuntwoman explains what she loved most about her job.

"There is nothing that feels more exhilarating or freer to me than the wind and sky rushing by me as the earth rolls around my head," the post says. "I'm alive up there. To soar like a bird and touch the sky puts me in a place where I feel I totally belong. It's the only thing I've done that I've never questioned, never hesitated about and always felt was my destiny."

She also answered a question she said she got frequently: What about the risk?

"I feel safer on the wing of my airplane than I do driving to the airport," she wrote. "Why? Because I'm in control of those risks and not at the mercy of those other drivers."

A program for the air show touted Wicker as a performer of "heart-stopping" feats who did moves that "no other wing walker is brave enough to try."

"Wing riding is not for this damsel; her wing walking style is the real thing," the program said. "With no safety line and no parachute, Jane amazes the crowd by climbing, walking, and hanging all over her beautiful ... aircraft.

"Spectators are sure to gasp as this daredevil demonstrates in true form the unbelievable art of wing walking," it says.

On the video of the crash, an announcer narrates as Wicker's plane glides through the air.

"Keep an eye on Jane. Keep an eye on Charlie. Watch this! Jane Wicker, sitting on top of the world," the announcer said, right before the plane makes a quick turn and nosedive.

Some spectators said they knew something was wrong because the plane was flying low and slow.

Thanh Tran, of Fairfield, said he could see a look of concern on Wicker's face just before the plane went down.

"She looked very scared," he said. "Then the airplane crashed on the ground. After that, it was terrible, man ... very terrible."

In 2011, wing walker Todd Green fell 200 feet to his death at an air show in Michigan while performing a stunt in which he grabbed the skid of a helicopter.

In 2007, veteran stunt pilot Jim LeRoy was killed at the Dayton show when his biplane slammed into the runway while performing loop-to-loops and caught fire.

Still, King said, in the four decades since Flying Circus started, many kids have been so inspired watching the show that they later became military and commercial pilots.

"Our show takes them back to the barnstorming era of air shows," he said. "It's amazing how many people have taken up aviation careers because of their first exposure to the Flying Circus."

___

Associated Press writer Verena Dobnik in New York contributed to this report.

___

Follow Amanda Lee Myers on Twitter at https://twitter.com/AmandaLeeAP

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-06-23-Air%20Show%20Crash/id-9c921c9687504b91bb5099097143a5b2

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Researchers prevent cancer spread by blocking tissue scarring

Friday, January 25, 2013

What to fear most if faced by a cancer diagnosis is the spread of the cancer to other parts of the body. This process called metastasis accounts for over 90% of cancer patient deaths and therefore is a strong focus for cancer researchers. Researchers at BRIC, University of Copenhagen have shown that the enzyme Lysyl Oxidase (LOX) can create a "scarred" microenvironment that enhances cancer spreading. By blocking activity of the LOX enzyme, the researchers succeeded in significantly decreasing metastasis in a model of breast cancer.

'When we inhibit the activity of LOX in our cancer models, we show a dramatic reduction in metastasis. This suggests that therapeutic targeting of LOX can keep the tumour microenvironment "healthy" and thereby decrease metastasis, says Associate Professor Janine Erler from BRIC, who has headed the research.

Metastasis of breast cancer cells in the lung

In humans, LOX is an enzyme that is produced in response to tissue injury or chronic inflammation in our organs. It reacts to damage signals and "glues" collagen molecules together to form the scar-like structure. The result can be a fibrotic environment. The new findings from Janine Erler's research group show that persistent injury to lung and liver results in a fibrotic microenvironment that supports the growth of new tumours, and thereby enhances metastasis of breast cancer cells to these organs. Blocking LOX prevents the formation of this fibrotic microenvironment, thereby preventing enhanced metastasis to these organs.

'It is well-known that signals from fibrotic tissues can enhance tumour progression and metastasis, but the underlying mechanisms have remained unclear - Our new results provide insight into the link between fibrosis and cancer progression. Such a biological understanding is crucial if we are to develop effective therapies preventing tumour metastasis, says PostDoc Thomas Cox from Janine Erler's laboratory, who undertook the experimental investigation.

Development of new anti-fibrotic therapies

Currently, LOX-targeting therapies are under development for use in the clinic against cancer, as it has been known for some while that metastatic tumours express increased amounts of LOX. Yet, the new results from Janine Erler's group are the first to show that LOX promotes distant metastasis through structural changes in the organ microenvironments in response to persistent injury. The next step for the researchers is to dig deeper into the mechanisms underlying the relationship between fibrosis and cancer metastasis, and also to test their findings in other cancer models such as gastric and colon cancer.

'Further, our study indicates that LOX-targeting therapy can be relevant not only for cancer patients, but also to prevent fibrosis in patients with chronic inflammation or patients who has been exposed to persistent organ injury. This opens up for an even wider applicability of our biological findings, which strongly motivates the basic research in my laboratory, says Janine Erler.

###

The results have just been published in the international journal Cancer Research (Cox et al, Cancer research, Jan 23, 2013).

University of Copenhagen: http://www.ku.dk

Thanks to University of Copenhagen for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/126450/Researchers_prevent_cancer_spread_by_blocking_tissue_scarring

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Polycom's Videoconferencing Business Unfazed by Ambitious ...

Okay, so we don?t have flying cars yet. But, we do have video conferencing. And, in growing numbers businesses are adopting video conferencing into their overall Unified Communications strategy. But, I?m not so bullish on the video conferencing market as most people might be. Why? Well one word??Cloud?.

Yes, Video is here to stay and will continue to be deployed more and more. But, what company in their right mind today would want to invest in a video conference or ?Telepresence? system that costs $100k +? I know, people will argue that ?you can set-up a conference room with intelligent cameras that follow the discussion, that produce high-quality HD video, that can see the entire room, etc., etc.

However, with the rapid adoption of Cloud services and the ?as a Service? model, I think you?re going to see video sold more as an add-on to Hosted PBX offerings. In fact, Polycom already recognizes this because many enterprise Hosted VoIP companies are already using their bridging equipment in their cloud environments making video bridges an ?as a Service? offer.

More and more people are becoming road warriors or work from home employees. With the advent of cloud based video bridges it makes location a moot point. That?s the beauty of the Cloud.

The discussion of image quality and intelligent cameras doesn?t outweigh the benefit of mobility. Most people would prefer to be untethered and unrestricted as opposed to sitting in a stuffy conference room.

The large players like Polycom, Cisco and LifeSize will continue to sell their equipment. I just think the face of their customer is going to change and the sales numbers will be coming more and more from the many enterprise hosted VoIP companies that are growing exponentially.

Source: http://www.vocalpointcg.com/polycoms-videoconferencing-business-unfazed-by-ambitious-startups-ceo-says/

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Yellow Raincoat: Leaked Justin Bieber Track?

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Be Careful When Rekindling a Relationship | Psych Central News

By Rick Nauert PhD Senior News Editor
Reviewed by John M. Grohol, Psy.D. on January 23, 2013

Apparently getting back together with an old boyfriend or girlfriend is a relatively common occurrence. Unfortunately, the practice could lead to problems.

A new study of relationship patterns finds that nearly half of older teenagers and young adults break up and get back together with previous dating partners.

Additionally, over half of this group have sex as part of the reconciliation process.

In the study, published in the Journal of Adolescent Research, Sarah Halpern-Meekin, Wendy Manning, Peggy Giordano and Monica Longmore studied data on 792 daters and cohabiters ages 17 to 24.

This age cohort is also known as ?emerging adults.? The researchers studied two relationship patterns specifically ? reconciliation with an ex, or breaking up and getting back together, and ?sex with an ex,? when couples break up, yet remain sexually involved.

Investigators found that approximately 44 percent of emerging adults who had been in a romantic relationship in the past two years had experienced at least one reconciliation with an ex-romantic partner.

Moreover, 53 percent of those who reported reconciliations also reported having sex with their ex.

Furthermore, racial minorities in particular were even more likely to experience reconciliation or sexual relationships with previous romantic partners.

These findings led study authors to discuss the implications of reconciliations with previous romantic partners. In their analysis, researchers warn that emerging adults who reconcile may be prone to a behavior pattern that involves cycling through relationship formation.

?Furthermore, having sex with an ex may be problematic because former partners can have difficulty moving on from an old relationship or building new romantic attachments,? they said.

Source: SAGE Publications

APA Reference
Nauert PhD, R. (2013). Be Careful When Rekindling a Relationship. Psych Central. Retrieved on January 23, 2013, from http://psychcentral.com/news/2013/01/23/be-careful-when-rekindling-a-relationship/50696.html

?

Source: http://psychcentral.com/news/2013/01/23/be-careful-when-rekindling-a-relationship/50696.html

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'Getting worse': Egypt's gays fear government crackdown - World News

Ahmed Youssef / EPA

Eighteen days of popular protest culminated in the downfall of Egyptian president Hosni Mubarak on Feb. 11, 2011.

By Duncan Golestani, Correspondent, NBC News

CAIRO, Egypt -- Maha remembers going to Tahrir Square on Jan. 25, 2011. The 27-year-old office worker only wanted to look around the Cairo intersection filled with thousands of protesters. But seeing Egypt's revolution unfold before her, she left to get friends and quickly returned. Without planning to, Maha became one of the highly visible gay men and women who took to the streets shouting for change.

"We don't get freedom anywhere. No voice, nothing," said Maha, who declined to give her surname "So, the first chance at revolution, we fought."

Nearly two years after the ouster of former leader Hosni Mubarak, Maha sits smoking a shisha with her friend Noor at a back-street cafe in downtown Cairo. Together, the women have made this location a "safe place" for gays, somewhere they can come and be themselves.

Unlike in other major cities around the world, there is no flag or signage to indicate this is a "gay" cafe. People know about it through word-of-mouth and the online forum, "Bedayaa." They talk about the time since the revolution with a weariness that contrasts with the excitement they initially felt.

Many of Egypt's gays and lesbians thought sexual freedom was on the horizon. "There was a moment of hope but the last few years has killed it," Maha says, adding: "Nothing much has changed, it is very hard." She is interrupted by Noor: "I think it is getting worse," she says.

The women remember sitting with gay male friends at another cafe three months after the revolution, when locals complained about it and called nearby military police, who then found make-up in the bag of one of the boys. They were all taken away for questioning for "making a mess" in the area.

Egypt has no specific laws banning homosexuality although there are plenty of ways to charge someone suspected of engaging in homosexual acts. Police will often charge gay people with "debauchery" or breaking the country's law of public morals. The election of an Islamist president in Egypt, and the passing last month of a new constitution, has also increased fears among the country's gay men and women that anti-gay legislation could soon be introduced. "We think in two or three months they will put a law to discriminate," Maha says.

Many others fear a government crackdown is only a matter of time. The most notorious pre-revolution attack on gay men took place in 2001, when Cairo police raided a Nile boat, arresting dozens of gay men. Along with others taken from the streets, they became known as the "Cairo 52." But now, the Muslim Brotherhood is not just a power to be appeased - it is the dominant power in Egypt's new government.

The natural instinct for most gay Egyptians is to try not to draw attention to themselves but taking part in the revolution has brought greater visibility -- at a cost. Alongside other minorities the gay community has been criticized for its role in the uprising.

Adel Ramadan, a legal officer at the Egyptian Initiative for Personal Rights, describes the derogatory language used to attack the groups that took to the streets. "After? the fall of Mubarak, the criticism of those groups has always contained a sexual element. Whether it's the women who are participating are called prostitutes or 'loose' women, or men are called homosexuals."

AP

The former Egyptian president faces charges of corruption and complicity in deaths of protesters.

Maha believes this kind of rhetoric has led to an increase in verbal abuse. She thinks some people feel emboldened to shout and call names, knowing the authorities will be on their side. A popular term with some members of the Muslim Brotherhood is "shewaz," a derogatory term for homosexuals that loosely translates as "perverts."

While gay advocacy organizations are active in other predominantly Muslim countries such as Lebanon, Egypt's support groups are not well organized and struggle to be heard. The Egyptian Initiative for Personal Rights is a human rights group that will talk about gays but this cause is not a priority for them. Another group that works with them asked that it not be named for fear of reprisals.

Despite their fears, gay life continues in Cairo. Men still meet on one of the city's bridges, and the Internet and social media help bring people together. Kholoud Bidak is an activist who is thinking of setting up an online forum. She was also in Tahrir Square in January 2011 and was stunned at the number of gay men and women at the heart of the protests. She has been disappointed in the two years that followed, but believes the gay community has at least gained recognition from human rights groups, which were previously uninterested. "They are finally starting to acknowledge LGBTs, 'oh, they were in the revolution since day one very, very effectively.' I thought that is very positive."

She remains scared by the anti-gay rhetoric from some politicians and clerics but tries to stay upbeat. "There is some hope," she says. "How? I don't know."

Related:?

Oasis of tolerance or 'Republic of Shame'? Two faces of gay life in Beirut

'Men don't have to worry about being caught': Sex mobs target Egypt's women?

In Egypt's elections, politics is a new family affair

Source: http://worldnews.nbcnews.com/_news/2013/01/23/16644770-getting-worse-egypts-gays-fear-government-crackdown?lite

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Mars rover Opportunity now in 10th year

The older, smaller cousin of NASA's huge Mars rover Curiosity is quietly celebrating a big milestone Thursday ? nine years on the surface of the Red Planet.

NASA's Opportunity rover landed on Mars the night of Jan. 24, 2004 PST (just after midnight EST on Jan. 25), three weeks after its twin, Spirit, touched down. Spirit stopped operating in 2010, but Opportunity is still going strong, helping scientists better understand the Red Planet's wetter, warmer past.

"No one could've imagined how good the exploration and scientific discovery would be for this vehicle, looking from the perspective of nine years ago," said John Callas, Opportunity's project manager at NASA's Jet Propulsion Laboratory in Pasadena, Calif. "It's been a phenomenal accomplishment."

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The headline-stealing Curiosity rover, for its part, touched down on Aug. 5, 2012, marking the next step in Mars exploration. The car-size Curiosity weighs about 1 ton ? five times more than either Spirit or Opportunity.

Long-lived rovers
Spirit and Opportunity were originally supposed to spend three months searching for evidence of past water activity on the Red Planet. The golf-cart-size robots found plenty of such signs at their separate landing sites, showing that Mars was not always the cold and arid planet we know today. [ Most Amazing Discoveries by Spirit and Opportunity ]

For example, in 2007 Spirit uncovered an ancient hydrothermal system in Gusev Crater, suggesting that two key ingredients for life as we know it ? liquid water and an energy source ? were both present in some parts of Mars long ago.

And Opportunity is currently inspecting clay deposits along the rim of Mars' huge Endeavour Crater. Clays form in relatively neutral (as opposed to acidic or basic) water, so the area may once have been capable of supporting primitive microbial life, researchers say.

"This is our first glimpse ever at conditions on ancient Mars that clearly show us a chemistry that would've been suitable for life at the Opportunity site," Opportunity principal investigator Steve Squyres, of Cornell University, said of the discovery at a conference last month.

The rovers rolled far beyond their 90-day warranties. Spirit finally stopped communicating with Earth in March 2010, after getting mired in soft sand and failing to maneuver into a position that would allow it to slant its solar panels toward the sun over the 2009-2010 Martian winter. NASA declared the rover dead in 2011.

But Opportunity keeps chugging along. It has put 22.03 miles (35.46 kilometers) on its odometer since landing on Mars ? just 1 mile (1.6 km) off the all-time record for most ground covered on the surface of another world. The Soviet Union's unmanned Lunokhod 2 rover holds that mark, traveling 23 miles (37 km) on the moon back in 1973.

The great engineering that allowed Spirit and Opportunity to keep roving for so long is a big part of the six-wheeled robots' legacy, mission team members say.

"These are magnificently designed machines," Callas told SPACE.com. "We really have greatly expanded the exploration envelope by having a vehicle that can not only last so long but stay in very good health over that time, such that we can continue exploring."

Still in good health
While Opportunity is showing signs of its advanced age, such as an arthritic robotic arm, the rover remains in good shape overall.

"Its health right now is miraculously good," Callas said.

Still, the rover team is treating every day as a gift at this point, knowing that Opportunity could conk out at pretty much any time. Indeed, the sun will rise one day without a message from Opportunity, and its handlers will have to face the rover's death and the end of an amazing mission.

"It's going to be hard; it'll be the end of a great era," Callas said. "But we'll have to remember that we've had such a good run."

Follow SPACE.com senior writer Mike Wall on Twitter@michaeldwall or SPACE.com @Spacedotcom. We're also on Facebook and Google+.

? 2013 Space.com. All rights reserved. More from Space.com.

Source: http://www.msnbc.msn.com/id/50575686/ns/technology_and_science-space/

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